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“However , despite association of the factor V G1691A ( factor V Leiden ) and prothrombin ( factor II ) G20210A mutations with venous thromboembolism and myocardial infarction [ 10 11 ] , neither mutation is strongly associated with risk of stroke [ 12 13 14 15 16 17 18 ] . Although a study of British adults found elevated levels of serum homocysteine to be associated with an increased risk of stroke [ 19 ] , a case-control study of a common polymorphism ( methylenetetrahydrofolate reductase [ MTHFR ] T677C ) that results in increased serum homocysteine concentrations found no difference between patients with stroke and controls in either genotype or allele frequency [ 20 ] . Because antiplatelet agents with different mechanisms of action can bring about significant reductions in stroke risk , several platelet receptor genes have been tested as candidate stroke susceptibility genes [ 21 22 ] . To date , however , no compelling evidence for an association between any platelet receptor gene polymorphism and risk of stroke has been found .”
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| Is lemon:example of | FN_Sense_9493 More... |
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